Dominique Langin Selected Research

Diglycerides

4/2013	High-fat diet-mediated lipotoxicity and insulin resistance is related to impaired lipase expression in mouse skeletal muscle.
6/2011	Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans.
9/2009	Influence of gender, obesity, and muscle lipase activity on intramyocellular lipids in sedentary individuals.

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Dominique Langin Research Topics

Disease

52	Obesity 03/2024 - 04/2003
43	Insulin Resistance 03/2024 - 02/2002
29	Weight Loss (Weight Reduction) 01/2022 - 02/2002
13	Type 2 Diabetes Mellitus (MODY) 01/2023 - 04/2003
12	Body Weight (Weight, Body) 12/2020 - 12/2005
9	Overweight 01/2023 - 09/2013
7	Inflammation (Inflammations) 01/2019 - 01/2013
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2019 - 02/2004
4	Fibrosis (Cirrhosis) 12/2016 - 01/2014
3	Neoplasms (Cancer) 06/2021 - 11/2008
3	Hypertrophy 01/2021 - 01/2014
3	Hyperinsulinism (Hyperinsulinemia) 11/2009 - 04/2003
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 08/2019
2	Prediabetic State (Prediabetes) 01/2023 - 01/2018
2	Non-alcoholic Fatty Liver Disease 01/2020 - 01/2016
2	Cachexia 05/2014 - 11/2008
2	Glucose Intolerance 04/2013 - 02/2012
1	Liver Diseases (Liver Disease) 03/2024
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2019
1	Burns 01/2018
1	Fibrosarcoma 09/2015
1	Hyperplasia 01/2015
1	Endotoxemia 05/2014

Drug/Important Bio-Agent (IBA)

19	Insulin (Novolin)FDA Link 03/2024 - 02/2004
19	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 06/2004
14	LipidsIBA 01/2021 - 04/2003
13	Proteins (Proteins, Gene)FDA Link 12/2017 - 02/2002
11	Triglycerides (Triacylglycerol)IBA 01/2021 - 10/2006
11	Fatty Acids (Saturated Fatty Acids)IBA 01/2019 - 01/2006
10	Messenger RNA (mRNA)IBA 01/2018 - 06/2004
9	LeptinIBA 12/2017 - 04/2003
8	Transcription Factors (Transcription Factor)IBA 01/2021 - 02/2002
8	Sterol Esterase (Hormone-Sensitive Lipase)IBA 06/2019 - 10/2004
7	Lipase (Acid Lipase)FDA Link 01/2019 - 06/2007
7	AdiponectinIBA 10/2013 - 12/2003
5	EnzymesIBA 08/2019 - 09/2005
5	CarbohydratesIBA 01/2018 - 02/2010
4	Biomarkers (Surrogate Marker)IBA 01/2023 - 09/2005
4	RNA (Ribonucleic Acid)IBA 01/2021 - 06/2007
4	AdipokinesIBA 01/2019 - 10/2006
3	Nonesterified Fatty Acids (NEFA)IBA 06/2021 - 10/2006
3	DiglyceridesIBA 04/2013 - 09/2009
3	CatecholaminesIBA 01/2012 - 11/2005
2	Insulin Receptor Substrate ProteinsIBA 03/2024 - 04/2013
2	Hormones (Hormone)IBA 03/2024 - 08/2010
2	Oleic Acid (Oleate)IBA 12/2021 - 06/2021
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 10/2006
2	CytokinesIBA 01/2019 - 11/2009
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2019 - 06/2013
2	Natriuretic PeptidesIBA 01/2018 - 12/2015
2	Dietary Fats (Dietary Fat)IBA 09/2017 - 01/2012
2	Branched-Chain Amino AcidsIBA 09/2017 - 01/2011
2	CollagenIBA 06/2015 - 01/2014
2	AntioxidantsIBA 03/2015 - 10/2014
2	Thioctic Acid (Lipoic Acid)IBA 03/2015 - 10/2014
2	LigandsIBA 05/2014 - 04/2009
2	Acute-Phase Proteins (Acute-Phase Protein)IBA 11/2013 - 02/2012
2	Retinol-Binding Proteins (Retinoid Binding Proteins)IBA 10/2013 - 06/2007
2	Interleukin-8 (Interleukin 8)IBA 06/2013 - 11/2009
2	Dietary ProteinsIBA 05/2012 - 01/2012
2	C-Reactive ProteinIBA 02/2012 - 07/2009
2	Interleukin-10 (Interleukin 10)IBA 11/2009 - 08/2005
2	Plasminogen Activator Inhibitor 1IBA 11/2009 - 08/2004
2	HydrolasesIBA 09/2009 - 10/2004
2	CalciumIBA 10/2006 - 12/2005
1	Purinergic Receptors (Receptors, Purine)IBA 03/2024
1	Thromboxane A2 (A2, Thromboxane)IBA 01/2023
1	Adenosine Triphosphatases (ATPase)IBA 01/2023
1	Epoprostenol (Prostacyclin)FDA LinkGeneric 01/2023
1	Pyruvate CarboxylaseIBA 01/2022
1	Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA 06/2021
1	Vascular Endothelial Growth FactorsIBA 06/2021
1	CholesterolIBA 01/2021
1	Niacin (Nicotinic Acid)FDA LinkGeneric 01/2019
1	Apolipoproteins MIBA 01/2019
1	Protein Isoforms (Isoforms)IBA 01/2019
1	HDL CholesterolIBA 01/2019
1	MicroRNAs (MicroRNA)IBA 01/2019
1	Blood Glucose (Blood Sugar)IBA 01/2018
1	Guanylate Cyclase-Coupled ReceptorsIBA 01/2018
1	ProteomeIBA 12/2017
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 09/2017
1	Aromatic Amino Acids (Aromatic Amino Acid)IBA 09/2017
1	Perilipin-5IBA 12/2016
1	Glycerol (Glycerine)FDA LinkGeneric 06/2016
1	9-tetradecenoic acidIBA 01/2015
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2015
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 12/2014
1	PrebioticsIBA 07/2014
1	Pioglitazone (Actos)FDA Link 07/2014
1	Sucrose (Saccharose)IBA 06/2014
1	AntibodiesIBA 05/2014
1	Toll-Like Receptor 4IBA 05/2014

Therapy/Procedure

12	Caloric Restriction 01/2022 - 02/2004
4	Glycemic Control 01/2021 - 12/2015
2	Bariatric Surgery 01/2021 - 01/2008
1	Therapeutics 01/2023
1	Endurance Training 01/2021
1	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2021
1	Carbohydrate-Restricted Diet (Low Carbohydrate Diet) 08/2017